Recent blog entries for demo
2006年中央电视台春节联欢晚会上,蒙古族歌手布仁巴雅尔和他的妻子乌日娜、 侄女英格玛演唱的《吉祥三宝》,令全国观众陶醉。但鲜人为知的是,《吉祥三宝》 并不是一首新歌,而是布仁巴雅尔1994年献给自己3岁女儿的生日礼物。
Steve Osfield George Hall Yes and of course Ester "married out" so why does one evocate ones daughters to be like Ruth and like Ester or Rachel for that matter -some-one that got her handmaid knocked up
吴稚晖曾自我标榜：“我是三民主义的忠实信徒，但把吴稚晖化了灰，也还是个 无政府主义的信仰者。”又说：“作为无政府主义者，官是一定不做的，但国事是一定要过问的。”他说他最佩服的是佐刘邦 兴汉室的张良，鞠躬尽瘁，一生不做官。吴稚晖一生确有许多做官的机会。他与孙中山私交颇厚，孙当中华民国临时大总统， 他与孙同室而居并榻而眠四载，没有向孙谋过一官半职。他助蒋介石“清党”成功，南京政府建立后，老蒋多次请他出山，他 均表示：“我是无政府主义者，脾气也不好，不敢当呀！”除当了几天国民革命军政治部主任外，身上只有“中监委”和国语 统一筹委会主席头衔，多为闲职。
尊敬的党和政府领导： 我的女儿2014年从华政毕业，响应李克强总理号召，走进了大学生创业的行列，结果发现被耍了。我要说两句： 中国共产党的政府是中国人民的政府，不是日本皇军统治中国，中华人民共和国是我们所有中国人民的祖国，不只是共产党的祖国，我们父辈和祖辈，也为中国共产党的江山抗过枪，上过战场，搞过土改，而今我们的后代选择在体制外生活，绝不不允许成为你们的奴隶。如果习总书记没有明白这个政府的官僚作风严重，把人民当猴耍，不仅不会让人民屈服，而且会让习总书记的中国梦变成我邓平红的白日梦，并且还可以推动我们的后代的进步。 正因为如此，我一直在让我的女儿接受这些磨练。原本许诺给大学生的补贴资金5000元，结果是欺骗，根本没有给我女儿，社保补贴也想方设法克扣，只有通过上访才给她完整支付。每个月税务催她递交各种表格是非常积极严肃，而现在注销这个公司却麻烦之极，拖延几个月都办不下来，一趟又一趟地提出各种要求。 感谢你们，共产党，磨练我的女儿，她可不像我的性子那么急躁。 好在我的女儿这四年来，一直主要跟我学习计算机和英语，没有做到什么生意，零报税，因为填的表格不同，也甚至需要交纳3000元的税，没有做生意，哪来的税？你们共产党真会设圈套啊，这就是鼓励大学生创业，诱骗没有社会阅历的年轻人上钩，然后让年轻人的父母交钱。 注销公司这么麻烦，还好这些年在跟我学电脑，要真是努力做生意了，甚至要被你们共产党坑害坐牢的。 你们共产党人是不是想让所有善良单纯的年轻人都讨厌你们，你们是不是想让习总书记失望？ 这样搞下去，习总书记仅仅依靠封锁网络，抓写抱怨文章的人能够让社会稳定？ 为何不建议习总书记派警察到每家每户收缴菜刀呢？ 我觉得像秦始皇那样采取株连九族的方法控制舆情就更好了，反正张良早就死了。 科技如此发达的二十一世纪，催缴人民的血汗积极无比，给人民办事就耍猴。 请记住，区委书记先生，我们都是六零后，请善待九零后，叫你们的共产党的工作人员善待九零后，这个世界不是我们的，是他们年轻人的。 我老了，我已经55岁了，你难道没有老吗？ 无论你们多么凶恶，阻挡不了年轻人的脚步。 幸好我的女儿没有做什么生意，随你们怎样捣浆糊，捣吧，继续捣吧，封锁舆论吧，封锁吧。逃亡美国的千亿富豪是曾经比你的官职还大的共产党安全局的人，蹲进牢里享福的是曾经管着所有警察的周常委。 赔本的生意没人做，杀头的买卖有人做，只要掌握权力就可以不劳而获享受极品富贵，掠夺海量财富，中国绝对不缺少野心家。而野心家首先盯着的是那些拥有巨额财富的官僚，不是老百姓，抓十万个老白姓掠夺的财富不如逮一个拥有几百亿资产的贪官。逮一千个老白姓，不如找一个家底厚实的处级共产党官僚查一查。 随便你们怎样折腾我女儿，她这四年都在 跟我学电脑计算和英语。 你们如果把自己当成了日本皇军，你们就要想想你们的子孙和你们的祖坟，将来可以安置在哪里了。 我们的祖辈在战场上曾经毫发未损，即便和美国人打仗也照样立新功，我们的父辈曾经为共产党做狗腿子兢兢业业，我们的基因有着极高的智商，有着无比的善良，有着巨大的勇敢。 中国这块土地，不仅仅是你们现这些当权者的，也是我们的，我们的祖先在这块土地上长眠了几千年。 你们敢耍我们，我们的后代将来就敢将你们的后代驱逐到火星上去。 你们敢邪恶对待我们，我们的后代将十倍邪恶回报你们。 们敢撒谎，像圣经中耶稣说的，伪君子们还没有帮助穷人，就在大街上高喊帮助穷人，我们的后代就以牙还牙，以眼还眼。 请记住邓平红的话。 我江西省第八名高考出来，在中国六所大学出身，在你们共产党的眼里，就是一个猴，我一家三口就进了八所大学，都是猴。 静安区的区委书记安如生是我们江西人，就是在我们老家镇上的铁路做工人，到上海铁道学院委培四年，就一路升官。 还有很多共产党的高官，我都清楚，他们的简历，在网上公开的，我的许多同学在你们的政府做高官，我和他们同窗共读的时候，我很清楚他们。 我更清楚“地富反坏右”被下放在我小时候生活的村庄的时候，他们的飞天本事是怎样连自己的家里都不会清扫的。 看看那些走上审判台的官僚，哪个不是一副熊样子！ 我曾经为了女儿的户口跑到陈良宇市委副书记面前，看他摇头摆尾的神态，江西一省的官员伸长了脖子想看看这位即将接替黄菊的上海一哥风采。等到吴志明出访美国的时候，我就立即判断他要蹲到哪里去了。 做委区党政首脑，无论你多么辛劳，你的政府大厅哪怕就一个行政人员把老百姓耍猴，老百姓被惹怒了，也就恨你。因为，是你给了那些行政人员这个耍猴大机会。如果我开个公司，员工跟客人吵架，客人不取消我这个公司难道还会去计较我的员工？ 我做老板就要赶紧开除员工，或者赶紧教育他们要善待客人，否则公司就没有生意，大家都要饿死了。 这个道理，你就不懂了。 我曾经被上海铁道学院那个中专出身大系主任陷害，我就恨透了黄菊和陈良宇，我误以为这里都是浙江人做官，就恨最大的浙江官，所以就恨陈良宇，我就诅咒他们要蹲进牢里，结果后来果然黄菊生病不出来了，陈良宇蹲进牢里了。 所以我就特别迷信。 共产党如果坑害人民，人民就会迷信，妖孽就会趁机而出，到时候，就像三国时期孙坚所恐惧的那个妖道就会出来惑众。 你们想清楚吧。 上海铁道大学挂牌的时候，市委副书记谢丽娟，铁道部长在台上说要把上海铁道大学在五年内办成华东一流的大学，我在台下说五年内倒闭，这个校门要关掉。警察说，这个校门永远不会关，因为是江泽民总书记题词的。 我说，江总书记在台上如果让千家万户安居乐业，他的题词万古流芳，如果害的民不聊生，不要说他的题词，就是他儿子江绵恒和江绵康，将来在哪里生活，都是未知数。因为， 我当时被害得不能聊生，是系主任害的。这个帐就算在江泽民总书记头上了， 虽然他和我一道都以交大母校为荣。 结果，不到五年，那个校门果然封闭了。这难道不是天意吗？ 我不开玩笑的，这是在信访中写的。 还有上海交大门口的汉白玉石柱，我坐在那里摸着石柱说：凡我受辱的地方要拆掉。结果后来果然拆掉了，华山路扩建，我过了十年，才发现那些石柱搬到闵行校区去了。 这难道不是天意吗？在不公正的社会，我信仰神灵。祈求神灵保佑。 这个世界有一样是公平的，就是老天爷，让我们每个人寿数都差不多，同时让那些善良的人们特别聪明和健康。 你看看我，天天晚上熬夜到两三点钟，头发还是乌亮的，因为我要帮助我女儿，我忧虑她的前途啊。我要帮助她学会做个好游戏，放到苹果商店去卖，到时候，成功了，出名了，能够被美国的苹果公司或者谷歌公司选中，到美国去工作，你共产党还能管她吗？ 你们不用善良管理中国社会，把创业的大学生当猴耍，而不是细心关爱，让党的政策像雨露春风，滋润大地，使大学生创业的热潮一浪高过一浪。 你们政府养着那么人，一个好几年没有几个生意的公司注销起来都要搞上几十轮回，几个月，你们政府的办事大厅养着那么多人，效率高不高？ 裙带关系让这个政府塞满了官僚的后代，为了混饭吃，所以大家干脆就懒政，要使做得有效率，一会儿就没事做了， 一堆人坐在大厅就显得难看。 最后，我还要谢谢你们磨练我的女儿，不用着急，我在为她做实验，她有时间给你们磨啊。我学好了再教她。
处理情况： 邓平红： 2017年12月15日，我局接到长宁区信访办转送的你于2017年12月15日通过长宁区《区委领导信箱》的来信（编号：网000147748）。 2017年12月28日，我局工作人员与你电话联系了解有关情况。 你提出“你女儿注册的公司（上海善居建筑装饰设计工程有限公司）拟注销，但因税务、社保等原因，注销麻烦之极”等相关事项。 现就你提出的有关事项答复如下： 1、关于公司注销，应根据《公司法》第十章关于“公司解散和清算”、《公司登记管理条例》第六章关于“注销登记”等法律规定执行，建议学习了解。 2、公司解散的，应成立清算组，依法履行清算义务，清理公司财产、债权债务以及税务、社保等事项。并在清算结束后，向公司登记机关提交清算报告等文件申请注销登记，经公司登记机关注销登记，公司终止。 如有疑问，可拨打（021）62113277-2011咨询。 特此告知。 上海市长宁区市场监督管理局
The birthplace of the legendary Salars - Camel Springs. Profile picture
As a literary style that can concentrate on the rich social life and express human emotions, poetry grows rapidly in the land of multi-ethnic and multicultural blending in Qinghai. The unique cultural background of the plateau nourishes the poets of various nationalities and enables them to sing their own nation and homeland in the name of poetry. When we follow the footsteps of poetry to observe the plateau of Qinghai, we find that poetry here contains a large capacity that contains the cultural characteristics of Han, Tibet, Tu, and Salar.
For the Salars with a great history of migration, the history of their nationality is actually a history of finding a home. According to legend, more than 700 years ago, the Salar ancestors, the ancestors, and the Afghan brothers led the tribes from Central Asia. Samarkand was forced to migrate eastward. After a long road of trekking and exploration, they finally found themselves on the banks of the Yellow River in the Qinghai Highlands. The home of the sanctuary has established a new home.
The unique endowments and temperament formed by the Salars in the process of searching for regenerative homes are not only the inexhaustible spiritual resources of the nation, but also the spiritual core of the Salar literature. Therefore, in the history of the development of Salar literature, there are many poets with poetic dreams. They inherit the memory of generations of generations and sculpt the memory into a spiritual epic of a nation.
Known as the "first person of the Salar literature", Qiufu, after experiencing the great joys and sorrows of life and the impact of Western modern thoughts, returned again and became the watchmen of the Salar spiritual homeland. In 1994, his group poem "Towards the Labyrinth" was composed of "The Song of the Combination - The Labyrinth Symbol". "Plate Image - Somewhere Terrain Abstraction", "Red Covered Mountain", "Dongfu Landscape - Magical Induction", "The Form of Heaven" Waiting for 9 poems. The group poems show the blending of contemporary Chinese and Western cultures with a grand image, but the inner cultural foundation of the poet determines his calm attitude towards foreign culture. In the "Reprinted Lands - The Last Indication", he wrote: "I no longer confused the mission of the ancestors' eastbound and created a heavenly model without verification. Sitting around the warmth of the sheep dung The quietness / ..." Obviously, the poet's sense of root-seeking is strong, and in the comparison of Chinese and Western cultures, in the open situation, obsessed with the pursuit of their own national culture, and actively conceived the form of oriental culture.
Perhaps influenced by the beliefs of the nation, perhaps as Qiufu said is the genetics, this watch on the spiritual home also appeared in the younger Salar poets. Following the footsteps of the older generation of poets, Martin, Ardiff Wing and Han Wende have also become contemporary poets in the Salars who use poetry to climb life and find cultural roots.
Martin's poems are named "The Recital and Elegy of the Homeland", which shows that "Homeland" is the theme of his creation. The meaning of "homeland" is carried out in two dimensions in the works: one is the real area of the "Salar" on the bank of the Yellow River in Qinghai, and the other is the nation formed by the great migration experience of "Salal" in history. The spiritual residence of blood, temperament and endowment. "His writing with the help of the history and culture of the Salars and the resources of real life forms is not only the instinctive identity of the national sentiment, but also a rational choice, a conscious choice for finding the basal point of Archimedes for his soul." Critic Sugawara said, "From another point of view, the spiritual home of the Salars is not the impact of the Camel Spring on the banks of the Yellow River. It is not the ancestral city of Samarkand, but that time. The long-distance migration path with regenerative nature is the Slatian Golden Bridge from the disaster to the paradise in the tribes of the tribes. This is a journey initiated by the Salar men, which reshapes The spirit and soul of the Salars. This is Martin’s other home..."
The two-year long poem "The Journey of the Holy Land in the Eastern Highlands", which was created by Martin for two years, was forced from Salar to bid farewell to the Samarkand city state of Central Asia where his ancestors lived, and to look at the eastern highlands in the collective. Then the journey of the migration of the Upper Clan began, until the tragedy and search of the nine deaths of the "heads for the head", found their reborn in the Camel Springs on the banks of the Yellow River, in "the voice of men" The twilight of the prayers, the twilight of the armpits, and the twilight of the carnival are coming to an end. Finally, the poet has meaningfully opened such a scene: "And outside the crowd of carnival / the saints alone on the mound / ... / the moon rises, the sacred as holy / water / philosopher rises, such as Flower buds / mysterious blooms / like seeds / ding when landing."
The saints who are alone on the mounds, retrospectively looking at the road of this migratory tribe, instilled their concern for the source of their nationality, their meditation on the road to regeneration, and their understanding of the power of God. The three important elements also constitute the collective psychological dimension of the Salar men. The long poem "May" and "The eulogy and elegy of life" show Martin's more open mind as a poet. He promoted the poetry from the recollection and gaze of his own history and reality to the realm of human universal emotion and the realm of human life itself.
The long poem "The Shipwreck" of the poet Ardiff Wings 988, "I know a river / this is the Yellow River / this is the eternal memory of the Salar / the river / and the distant sound / ... / the sky at the moment The plains of the wilderness are quiet/late winter, and the tears of the river are flowing in the hills. The direction of the people is still the direction of the river..." Explaining a Salar hero who pursued his life in pursuit of his ideals. He drove a ship from ancient times. A nation has experienced hardships and obstacles and finally gained a bright future. This poem has a strong sense of root-seeking and humanistic feelings, and it contains a unique realism spirit.
Another young Salar poet, Han Wende, wrote in his more than 500 long poems, "The Flames of the Flames,": "Which white horse is wearing a fiery red glow? Which big hand is flashing black? The light / give back the brightest white sails to us / ... / make all the hearts filled with flowers / make this shore or the other shore filled with waves of swear words / faint moments / is the other world that lifted the shoulders /... "In the fifth chapter of "Sorrowful Song", I wrote: "In fact, we seem to have walked through this sunken road / roadside stone and weeping grass leaves / dancers and singers who make the light as clouds Touched / gently answered the fear of the soul / I stood straight on this road but I feel empty / I seem to have lost something / ... / Where to finally go / knees and the eyes of the old man / shock The bronze sound of Haoyu/Answer: You should be at home with yourself."
In Han Wende's poems, we also saw a lot of writing about the Yellow River of the life home: "The world is far away / only me and the Yellow River / lovers like a pair of kisses" "The blood of the Yellow River is my blood / the call of the Yellow River It’s my call. “Let’s lean over this river/I can’t say anything/a stone’s squatting posture is deep.” “I grew up in the Yellow River and knew it but it took a lifetime/I found myself for the first time. The heart is full of waves. I believe that I am also very deep for the first time. I am struck by the heart of the Yellow River. I will hit the Yellow River with a heart that loves you. You will mature a lot / you will be a lot stranger." He completed the beauty of his homeland with the image of the Yellow River, and also made readers remember that in the plateau valley, there is a ethnic group closely related to the Yellow River - the Salar.
Along the way, on the road of poetry, Han Wende has been able to navigate from the original small test knives to the grand narrative of the epic theme. We have seen that the national poet has found the home of his own and his homeland in the territory of poetry. Poetry is the home of his soul, and the Yellow River is the home of his life with the Salars. In many epic national narratives, he has revealed the rich psychological characteristics and national character of the Salars from different aspects, so that more people understand the deep feelings and awe of this nation for nourishing their Yellow River.
Han Wende's "Prayer of Ramadan" continues his long poetry style. This 600-plus-word poem is shocking: "Human, how can you hold your dreams in your hand?" ?/ How can you shape yourself into a golden body? / How can you call the wind and rain? How can you open up the sky? / Time in front: Everything is just a night of dust." When poets choose poetry, they choose the way and means of understanding the world and dialogue with the world at the pure height of spiritual culture. The continuous exploration and exploration in the field of poetry has turned Han Wende's poetry from the original homeland to a kind of introspection and questioning of the soul, which makes people feel the tenacity of the Salar nation and also feels a greatness from the whole humanity.
It is this recollection of national history and the re-construction of historical memory that has made the Salar poetry always have a grand narrative construction, and has a strong humanistic feelings, coming from history and staying in history. . From Qiufu, Martin, Ardiff Wings to Han Wende, these Salar poets use their homeland as their poetry background, and in their infinite charm and imagination, they express their national sorrow and beauty with unique expression. It is the infiltration and infiltration of this unique national cultural background that makes the Salar poets present a collective poetic writing of their own culture. In the grand historical construction, these verses show the strong pride and mission of the whole nation, thus forming the unique personality and atmosphere of the Salar literature.
(The author is an associate researcher at the Institute of Literature and History, Qinghai Academy of Social Sciences)
Preamble: Cooperation or betrayal is the plight of famed prisoner's dilemma now facing China and the United States. Although cooperation is in the best interests of both parties, rational calculations and human selfish nature will make them choose to betray. The prisoner's dilemma clearly proves that in a non-zero sum game, cleverness is stupidity, and Pareto optimality and Nash equilibrium are incompatible.
The Sino-US trade war began, and its outcome depends on the game between two sides. The best outcome is that both sides adopt a tit-for-tat strategy, and base their likeness with undue stress to construct a win-win cooperation. The worst outcome might be that both sides recognize that the opposing side is aided by a devilish contempt, and finally all hell break loose, and they both become the devil seeing from the other side.
Electrophysiology Devices Market Growth Intensifies on Heels of
8:55 AM ET 8/20/18 | PR Newswire
PALM BEACH, Florida, August 20, 2018 /PRNewswire/ --
MarketNewsUpdates.com News Commentary
The development of the worldwide Electrophysiology market is being driven by a few elements, the most essential of which is the technological advancements. Technological developments and progressions of innovation have prompted the introduction of new products and devices in a Global Electrophysiology Market which is expected to exceed more than $8.5 Billion by 2024 at a CAGR of 10.6%. With the increasing incidence of atrial fibrillation (AF), the electrophysiology (EP) market is expected to grow rapidly over the next few years and believed to be one of the prime factors for the EP market to continue to flourish and become one of the most rapidly-growing areas of healthcare. Active healthcare stocks in news today include: BioSig Technologies, Inc. (OTC: BSGM), Medtronic plc (NYSE:MDT), Boston Scientific Corporation (NYSE:BSX), Abbott Laboratories (NYSE:ABT), Johnson & Johnson (NYSE:JNJ).
BioSig Technologies, Inc. (OTCQB: BSGM) BREAKING NEWS - BioSig Technologies, after announcing last week that the Company has received 510(k) clearance for its first product, PURE EP System, from the U.S. Food and Drug Administration (FDA) the Company, a medical device company developing a proprietary biomedical signal processing platform designed to address an unmet technology need for the $4.6 billion electrophysiology (EP) marketplace, today announced that it has partnered with Mrs. Amy Ansfield Scott in order to assist with nationwide KOL engagement ahead of the commercial launch of PURE EP(tm) System in the U.S.
Mrs. Scott brings to the Company over 30 years of experience in medical devices, including over 20 years in electrophysiology (EP). Most recently, she served as Director of Strategic Partnerships for Biosense Webster (Johnson & Johnson), a role which she was responsible for primarily U.S. engagement of physicians and management of the company's Scientific Advisory Board. Prior to that role, Mrs. Scott was managing a team responsible for driving customer engagement and education, including development of product demonstration and training sites, management of key accounts and liaison between internal clinical and field clinical trials teams. During her career with Biosense Webster, Mrs. Scott also served as Global Product Director for Atrial Fibrillation, the role in which she developed, executed and managed EP/Afib Centers of Excellence. She brings to BioSig extensive experience in defining customer needs and promoting key account relations and activities.
"An experienced and passionate leader like Amy is an invaluable addition to our team. Her expertise in building successful physician relationships and the depth of her marketing knowledge can significantly benefit our effort to launch and expand our clinical operations following our 510(k) clearance," stated Mr. Kenneth Londoner, Chairman & CEO of BioSig Technologies, Inc.
The Company announced that it received the 510(k) clearance for its PURE EP System on August 14, 2018. Earlier in the month, on August 1, 2018, the Company announced its intentions to list on the Nasdaq stock exchange.
"I'm delighted to join the BioSig team as the Company starts a new chapter. I have been impressed with the strong value proposition of PURE EP and the long-term vision of the management team. I look forward to helping the Company make its first steps in the clinical field," commented Mrs. Scott. Read this and more news for BioSig Technologies at: http://www.marketnewsupdates.com/news/bsgm.html
In other healthcare industry news of note:
Boston Scientific Corporation (NYSE:BSX) recently announced it has recently closed its acquisition of Claret Medical, Inc., a privately-held company that has developed and commercialized the Sentinel(R) Cerebral Embolic Protection System, the only device cleared to protect patients against the risk of stroke in transcatheter aortic valve replacement (TAVR) procedures. The company also announced that the U.S. Centers for Medicare and Medicaid Services (CMS) granted a New Technology Add-on Payment (NTAP) designation for the Sentinel System as part of the federal fiscal year 2019 Inpatient Prospective Payment System (IPPS). The NTAP designation, awarded to new medical devices determined to substantially improve the diagnosis or treatment of Medicare beneficiaries, will be effective on October 1, 2018.
Medtronic plc (NYSE:MDT) recently announced the online publication of `Effect of intrathecal baclofen on pain and quality of life in post-stroke spasticity: a randomized trial (SISTERS)` in Stroke: A Journal of Cerebral Circulation (Stroke). These results, secondary endpoints of the `Spasticity In Stroke-Randomised Study` (SISTERS) trial, demonstrate Intrathecal Baclofen Therapy (ITB Therapy(SM)) with Lioresal(R) Intrathecal (baclofen injection) reduces spasticity-related pain and improves quality of life more than conventional medical management (CMM) with oral antispastic medications. "Despite its known benefits, ITB Therapy continues to be underused when it comes to treating severe spasticity in post-stroke patients," said lead author and study investigator Michael Creamer, D.O., of Central Florida Pain Relief Centers in Orlando, Fla. "These secondary study results demonstrate that, in addition to treating excessive muscle tone associated with spasticity, ITB Therapy also addresses spasticity-related pain and quality of life and should be considered when assessing treatment options for post-stroke spasticity."
The Janssen Pharmaceutical Companies of Johnson & Johnson (NYSE:JNJ) announced recently the submission of a supplemental Biologics License Application (sBLA) to the U.S. Food and Drug Administration (FDA) and a Type II Variation to the European Medicines Agency (EMA) seeking approval of a split dosing regimen for DARZALEX(R) (daratumumab). The applications seek to update the Prescribing Information and Summary of Product Characteristics to provide health care professionals with the option to split the first infusion of DARZALEX(R) over two consecutive days. The submissions are supported by data from the Phase 1b MMY1001 clinical trial, which demonstrated DARZALEX(R) pharmacokinetics (PK) concentrations were comparable regardless of whether the first dose was administered as a split infusion or single first infusion in patients with multiple myeloma. The safety profile of DARZALEX(R) was comparable when administered initially as a split or single dose. "We are committed to exploring options that may improve the administration profile of DARZALEX(R) and the overall treatment experience for patients and physicians," said Craig Tendler, MD, Vice President, Clinical Development and Global Medical Affairs, Janssen Research & Development, LLC.
In an article published by MD+DI Qmed, the FDA recently cleared Abbott Laboratories' (NYSE:ABT) Advisor HD Grid mapping catheter with the company's Sensor Enabled technology. The company said the Advisor HD Grid employs a new design that allows physicians to see things differently, capturing and analyzing data in a new way to create highly detailed maps of the heart that better differentiate healthy tissue from unhealthy tissue. The new mapping catheter builds on Abbott's other cardiac mapping technologies, including the EnSite Precision system that the company inherited through its acquisition of St. Jude Medical. According to Abbott, the Advisor HD Grid is designed to capture information that is often missed with standard mapping catheters, such as the direction and speed of cardiac signals. The device offers a unique grid configuration intended to capture this information and enable the creation of high-density maps of cardiac tissue to support optimal treatment for patients, the company said.
DISCLAIMER: MarketNewsUpdates.com (MNU) is a third party publisher and news dissemination service provider, which disseminates electronic information through multiple online media channels. MNU is NOT affiliated in any manner with any company mentioned herein. MNU and its affiliated companies are a news dissemination solutions provider and are NOT a registered broker/dealer/analyst/adviser, holds no investment licenses and may NOT sell, offer to sell or offer to buy any security. MNU's market updates, news alerts and corporate profiles are NOT a solicitation or recommendation to buy, sell or hold securities. The material in this release is intended to be strictly informational and is NEVER to be construed or interpreted as research material. All readers are strongly urged to perform research and due diligence on their own and consult a licensed financial professional before considering any level of investing in stocks. All material included herein is republished content and details which were previously disseminated by the companies mentioned in this release. MNU is not liable for any investment decisions by its readers or subscribers. Investors are cautioned that they may lose all or a portion of their investment when investing in stocks. For current services performed MNU has been compensated seventy six hundred dollars for news coverage of the current press release issued by BioSig Technologies, Inc. for the week's coverage by the company. MNU HOLDS NO SHARES OF ANY COMPANY NAMED IN THIS RELEASE.
(MORE TO FOLLOW) Dow Jones Newswires
August 20, 2018 08:55 ET (12:55 GMT)
Electrophysiology Devices Market Growth -2-
Media Contact email:
Nio hopes to raise up to $1.5 billion, making it the fourth largest IPO in the U.S. this year
Nio Inc., a Shanghai-based electric-car maker, has filed for an initial public offering, hoping to raise money for an expansion that includes launching a smaller electric SUV to broaden its customer base.
Nio earlier in August filed to offer about $1.8 billion worth of American depositary shares. According to an amended filing Tuesday, the company set the terms of its IPO, seeking to sell 160 million shares between $6.25 and $8.25 per American depositary share to raise up to $1.52 billion, if an option to sell more shares is exercised.
If Nio succeeds in raising that sum, it would mark the fourth largest U.S. IPO this year, behind Axa Equitable Holdings' (EQH) $3.16 billion, PagSeguro Digital's (PAGS) $2.6 billion, and iQIYI Inc.'s (IQ) $2.4 billion.
The company expects to list its ADS on the New York Stock Exchange under the ticker symbol NIO, and Morgan Stanley, Goldman Sachs and J.P. Morgan are among the underwriters.
Entities affiliated with Chinese technology conglomerate Tencent Holdings Ltd. (0700.HK) have a 15% stake in Nio, and those affiliated with investment powerhouse Hillhouse Capital another 7.5%, according to the company's prospectus. Founder and Chief Executive Bin Li holds a 17% stake.
The company will compete with Tesla Inc. (TSLA) in the luxury electric-car market, and mentioned the potential U.S. rival 13 times in its prospectus.
Here are five things to know about Nio ahead of its IPO:
Its name means 'blue sky coming'
Nio's Chinese name, Weilai, translates as "blue sky coming." Li founded the company in 2014, then named NextCar Inc. It changed its name to Nio three years later.
Nio first introduced a "super car," the EP9, in 2016. It launched its first volume-produced car, the ES8, in December 2017, with deliveries starting in June of this year.
The ES8 is a 7-seater all-aluminum body electric SUV that the company boasts is cheaper in China than Tesla's Model X.
"Currently we believe no premium BEV is available to Chinese consumers at competitive pricing and the ES8 is expected to face limited competition initially from premium BEVs," NIO said in the prospectus.
As of the end of July, Nio had delivered 481 ES8s and had unfulfilled reservations for more than 17,000 ES8s with deposits, according to the prospectus.
Nio plans to launch its second vehicle, the ES6, by the end of 2018, and start deliveries in the first half of next year. The ES6 is a 5-seater, "high-performance premium electric SUV, set at a lower price point than the ES8 to target a broader customer base," NIO said in the filing.
Nio had a fairly standard warning about the ES6 in the filing, saying it "may not successfully develop the ES6. Our vehicles may not meet customer expectations and our future models, including the ES6, may not be commercially viable."
No revenue until this year
Nio has more in common with Tesla than ambition: it also has lost massive amounts of money and burned through piles of cash -- part of the reason it plans to go public.
"We have negative cash flows from operation, have only recently started to generate revenues and have not been profitable, all of which may continue in the future," it warned.
Nio began showing revenue this year, reporting $6.7 million in vehicle sales and $7 million in total revenue for the first six months of 2018, when net losses topped $502 million. The company reported a net loss of $758.8 million for all of 2017.
Through June, Nio had burned through $549 million in cash to operate, compared with $691 million for all of 2017. Capital expenditures hit $163 million in the first six months of this year, compared with $168 million for all of last year.
The company estimates that its capital expenditures for the next three years will reach about $1.8 billion. That includes money for improvements and installation of equipment at a plant in Shanghai, as well as for research and development and the expansion of its sales and service network. It expects to incur about $600 million of that in the 12 months starting July 2018.
Nio's total borrowings, as of June, reached $189.9 million, mainly bank loans and a loan from its investors, said the prospectus.
'Limited experience' in making cars
There is no dearth of risks listed in Nio's prospectus, and such risks are familiar to anyone who has spent any time reading about Tesla: "Our ability to develop and manufacture a car of sufficient quality and appeal to customers on schedule and on a large scale is unproven and still evolving," it said of risks relating to business.
Nio admits it has "limited experience" so far in high-volume manufacturing of electric vehicles.
"We cannot assure you that we will be able to develop efficient, automated, cost-efficient manufacturing capability and processes, and reliable sources of component supply that will enable us to meet the quality, price, engineering, design and production standards, as well as the production volumes required to successfully mass market the ES8 and future vehicles," it said.
Then there are the suppliers. The ES8 uses more than 1,700 purchased parts which Nio buys from more than 160 suppliers. Many of those are single-source suppliers for these components, and the company is expecting that this will be similar for the ES6 and any other future vehicle it may produce.
"The supply chain exposes us to multiple potential sources of delivery failure or component shortages," says the prospectus.
The company is also highly dependent on government incentives and policies that are favorable for electric vehicles.
Its business could be affected by trade wars
Nio said its business could be "adversely affected" by trade tariffs or other trade barriers, including U.S. tariffs imposed in March on steel and aluminum and additional tariffs targeting Chinese goods.
Nio does not export any products to the U.S. and it is not yet clear what impact these tariffs could have. It intends to sell its cars only in China at least in the near future, but tariffs could potentially impact raw-material prices, it said.
Unusual--and risky--corporate structure
Like many Chinese companies with listings outside of China, Nio is a variable-interest entity, or VIE, a structure created in the 1990s as a workaround for Chinese companies that are not allowed to have direct foreign ownership.
Under the VIE structure, the Chinese company creates two entities, one in China that holds the permits and licenses needed to do business there and the other an offshore entity, in this case in the Cayman Islands, in which foreign investors can buy shares. The Chinese entity, which is usually owned by top executives, pays fees and royalties to the offshore company in contractual arrangements.
The biggest example of a VIE is Alibaba Group Holding Ltd., in which the Chinese entity is wholly owned by its founder and chairman, Jack Ma.
The risk with this setup is that foreign investors don't actually own stock in the company, and local management or even the Chinese government could decide or force a split with the listed company, leaving U.S. investors high and dry.
"It is uncertain whether any new PRC laws or regulations relating to variable interest entity structures will be adopted or if adopted, what they would provide," the company warns in its prospectus.
As an "emerging growth" company, Nio has to follow fewer reporting and other requirements.
-Claudia Assis; 415-439-6400; AskNewswires@dowjones.com
Sally Schuman翻译 ( presumably from René Viénet’s preface, originally written in French?)
众所周知，中国(于二十世纪）发生了一场革命。人们普遍以为它发生在1949年，而不是1925年的中国社会的大变异。《中国革命的悲剧》，是由一位马克思主义者写成，是对这场无产阶级革命的历史回首; 是对其失败的分析。 1937年，托洛茨基撰写了本书第一版的序言。最后一个布尔什维克者从布尔什维克的最后一次革命中得出了他的结论。三十年来，没有一位记者，汉学家或历史学家将这本书翻译成法语。随着斯大林的死亡，那些作为其战略附庸的人仍然不希望看到共产国际在中国，西班牙和其他地方的角色被曝光。为了使他们的职业生涯永久化，有必要尽可能长时间地继续人民阵线的神圣联盟和战后时期，当时的爱好者和苏联的批评者同意承认其作为“社会主义国家”的地位，很高兴地看到，简而言之，无产阶级革命只不过是那样。
艾萨克（Issac) 的书应该改变所有读者对人类命运的理解认识。事实上，从第四章到第十七章，艾萨克斯叙述了马尔罗( Malraux) 从双筒望远镜的错误端看到的东西。所有价值观的来源，真实的历史，也是所有真理的源泉; 正如他在1949年的结语中心甘情愿地承认的那样，马尔罗的书籍“只是表面上与历史有关”。犹如作者去游泳玩水，不巧一本书浮出了水面，那是因为他匆匆消化了与当时欧洲间接相关的某些价值（以及其中的戏剧），并将它们变成了文学：罗曼蒂克的意识逃离了真实的历史。中国革命（以及人类的命运）是通过想象自我的凌驾于中国无产阶级自身实践的上层意识的东西。马尔罗的“实践”反对真正的实践。但是，当我们拟定说谎者和谎言的清单时，谈论讲故事者的缺点只是一个细节。在这方面，读者将欣赏哈罗德·艾萨克的澄清工作。如果译者必须写一个序言，在这种情况下，他必须致力于纠正法国书籍创作的形象，甚至在译者动笔翻译之前。
《中国革命的悲剧》不是托洛茨基主义宣传的作品。艾萨克斯显然放弃了列宁主义。然而，他并没有把他的研究结束到一个更具启发性的激进主义，也没有在中国的布尔什维克革命中发现想引导革命的官僚机构与革命群众之间的对立的战线。 Harold Isaacs自己收集的文件几乎已经足够了。但他没有考虑这个问题以及其他几个问题，因此他的书对于知情读者来说有点过时了。对于其他人，没有。在作者决定翻译的版本中，几乎完美无缺，“中国革命的悲剧”是一本可与法国内战相媲美的历史书。当然，这是一本以争吵和争吵时代为标志的书 - 斯大林 - 托洛茨基的对抗 - 布尔什维克权力对其官僚后代的残余。但是，中国革命正是在这场对抗中找到了必要的登场景致。它客观上是中国本身的同类型对抗，但在这场革命景致中存在着应运而生的不同演员的荒谬的差异。
自艾萨克的书以来发表的所有严肃作品都承认了对他的分析的借鉴。如果法国不是这样的话，那是因为没有一篇关于中国革命的认真工作已经得以出版。辩证理性的沉睡让人浮想出妖魔鬼怪，而法国则是人们坚持冷静的配方将马克思主义视为一种意识形态，把中国视为共产主义的实践与行动 - 这是对这些问题的最倒退的偏见。找到一家出版商已经花了三十年的时间，但在中国，特定的官僚权力在1925年至1949年之间崭露头角。专家对此感到困惑。他们没有理解当代中国的必要基础。他们对马克思主义一无所知，他们毫不犹豫地相信毛泽东思想是一个亚洲真理。在这种情况下，人们不仅要不知道中国有马克思主义者，而且必须永远不要读马克思。通常他们也没有读过艾萨克斯（也没有任何其他美国人以最低的严谨性研究过这个问题）并且不知道周恩来参与了所有连续独裁统治的所有错误，借中国共产党之手。或者毛泽东有一个值得怀疑的优势，即从“工人阶级”的最高领导地位，最终沉没于农民起义的土豪加-军痞行为，在中国，他能够在1945年至1949年之间投入运作 官僚机器- 在这里找到了李济申，在那里，中国农民和工人中最邪恶的屠夫唐晟 - 获得了民族主义者真正堕落的权力。在这场失败的遗产中，有一个可以是共产主义者，社会主义者或受大众拥护的中国人民的领袖，但其号招力只局限于那些文人骚客的生计依赖与对一种欺骗的细致及宗教性的热诚。对于那些耸人听闻的作家来说，“社会主义权力”的谬论是亲爱的，因为这是他们唯一被认可的专业，他们在西方唯一的社会功能，他们勤劳的活动资格。这个中国独裁统治的最荒谬的叙述已被放之五湖四海。世人很高兴地认为该政权是非暴力的，与斯大林主义俄罗斯相反。但同样忠诚的人否认在俄罗斯存在集中营。所有这一切，直到“文化大革命”。后者将至少具有显示那些不了解官僚“整体主义”意义的人的优势，如果官僚主义力量 - 即对生产力的官僚权力，当然还有生产力作为对自然的社会权力 - 他们自己是独立的，脱离了那些将他们组成一个独立世界的人，其原因在于他们的形式是相互对立的官僚;而他们的形式只是在这些官僚的关系和联系中才是真实的。因此，这种官僚力量的整体自由化，可以说是一种客观形式，不再是官僚的力量，而是官僚机制的力量。在过去的一段时间里，官僚力量对形式如此无动于衷。官僚就是这样。在目前的危机中，统治阶级的分裂与绝对认同意识形态（与统治者的统治）的典范相结合，制度的抽象谵妄使其接近自己的自我毁灭。威胁所有没有他们的官僚。内部腐烂的东西在外面没有任何好转。当中国谴责“新的莫斯科沙皇”，而俄罗斯在北京认识到“满族王朝的延续”，那一刻，在中国本身，在经济和国家机器彻底崩溃的情况下，毛泽东最终证明了毛泽东错了，显然官僚权力的悲剧已经开始了它的最后一次滑稽的展览。辩证法的冒险永远不会结束。
translated from English. All Rights Reserved by 'Laird Unlimited LLP'
01. The Music of The Night (夜的乐章)
02. Vino de Amor (爱情酿的酒)
03. A Twist of Fate (命运之转折)
04. Brave New World (美丽新世界)
05. Love of My Life (我一生的爱)
06. Glitter And Dust (绚丽与尘埃)
07. Plaisir D’amour (爱的喜悦)
08. Forever Bound (一世情结)
09. The Vision (幻影)
10. Recuerdos De La Alhambra
11. Careless love (浅爱)
12. She’ll Never Know (她永远不会知晓)
2 older entries...